Scalable Large Volume Magnetic Bead Separators
Sepmag Q and Sepmag N large volume magnetic bead separators provide reliable, scalable magnetic bead separation for liter-scale batch processing in diagnostics, therapeutics, and industrial biomanufacturing.
When production departments scale up magnetic bead workflows, they face challenges in throughput, reproducibility, and regulatory compliance. The Sepmag Q and Sepmag N scalable large volume magnetic bead separators are engineered to overcome these challenges – delivering consistent separation conditions, real-time monitoring, and validated scalability from milliliters to tens of liters.
Introducing Sepmag Q
and Sepmag N scalable large volume magnetic bead separators
Both Sepmag Q and Sepmag N systems offer the same robust performance and real-time process control, for both glass and plastic bottles, across a wide range of volumes.
Feature | Sepmag Q Series | Sepmag N Series |
Bottle Type | Glass bottles | Plastic bottles |
Ideal Use | Standard bioprocess vessels | Lightweight, flexible integration |
Volume Range | 1-50 liters | 1-50 liters |
Software | QUALITANCE | |
Applications | Nucleic acid extraction, protein purification, cell isolation, diagnostics | |
Sepmag Q Series – Glass Bottle Magnetic Bead Separator
Purpose-built for efficient, high-yield separations in glass vessels, Sepmag Q magnetic bead separators are trusted for large-scale workflows requiring robust quality control and validated consistency.
Dimensions and weight | Caution distances | ||||||
Model | ø int | ø ext | L | H | Weight | Radial | Vertical |
sepmag Q1L | 111 mm | 228 mm | 494 mm | 152 mm | 23 Kg | 91 mm | 126 mm |
sepmag Q2L | 155 mm | 332 mm | 648 mm | 161 mm | 46 Kg | 148 mm | 197 mm |
sepmag Q5L | 195 mm | 372 mm | 696 mm | 205 mm | 68 Kg | 184 mm | 233 mm |
sepmag Q10L | 237 mm | 462 mm | 826 mm | 264 mm | 138 Kg | 194 mm | 319 mm |
sepmag Q20L | 298 mm | 580 mm | 986 mm | 356 mm | 298 Kg | 335 mm | 390 mm |
Sepmag N Series – Plastic Bottle Magnetic Bead Separators
The Sepmag N large volume magnetic bead separator offers the same magnetic performance as Sepmag Q but is designed for use with plastic vessels – ideal for lightweight setups, disposable containers, or cleanroom workflows.
Dimensions and weight | Caution distances | |||||
Model | ø int | ø ext | H | Weight | ø | H |
sepmag NF250ml | 70 mm | 174 mm | 110 mm | 7 Kg | 305 mm | 288 mm |
sepmag NF500ml | 80 mm | 176 mm | 152 mm | 11 Kg | 338 mm | 313 mm |
sepmag N1L | 98 mm | 208 mm | 152 mm | 15 Kg | 435 mm | 340 mm |
sepmag N2L | 125 mm | 286 mm | 201 mm | 44 Kg | 569 mm | 550 mm |
sepmag N5L | 165 mm | 333 mm | 249 mm | 68 Kg | 706 mm | 654 mm |
sepmag N10L | 255 mm | 540 mm | 264 mm | 206 kg | 1070 mm | 960 mm |
sepmag N20L | 295 mm | 580 mm | 356 mm | 331 kg | 1250 mm | 1135 mm |
Core Benefits
The Sepmag Q and N systems are built on the same core design principles that enable safe, efficient, and scalable magnetic bead separation at large volumes. Both product lines support standardized, reproducible workflows from pilot-scale development to full-scale production, delivering the following key benefits:
Eliminate assay variability
Homogeneity, consistency and reproducibility.
Highest recovery of biomolecules and beads
Minimal material loss.
No re-suspension problems
Minimum aggregation.
Easy scale-up
No process re-engineering and no need to revalidate.
Quality Assurance
Monitor and record separation process.
Easy validation
Safe operation
No maintenance and operating costs.
QUALITANCE: Real-Time Process Validation Built In
All Sepmag Q and N large volume magnetic bead separators feature QUALITANCE, an integrated monitoring system combining software and optical sensors to control, document, and improve every step of your separation process.
Key Benefits:
Compare actual performance vs. defined protocols
Identify and correct issues before they impact results
Maintain traceable digital records for QA/QC
Export data for audits, regulatory filings, or internal reporting
Clients
Trusted by leading life science companies:
Questions & Answers
What are Large Volume Magnetic Bead Separators?
Large Volume Magnetic Bead Separators are engineered systems designed for efficient, high-throughput magnetic bead separation at multi-liter scales, supporting bioprocessing, diagnostics, and industrial manufacturing workflows. They enable scalable separation from pilot to production volumes with reproducible, high-yield results.
How do Sepmag Large Volume Separators support scalable bioprocessing?
Sepmag systems maintain consistent separation conditions across the entire working volume, eliminating the need for process re-engineering during scale-up. This ensures reproducible workflows from small batches to tens of liters with minimal method adjustment.
What makes Sepmag Large Volume Magnetic Bead Separators different from traditional separators?
Sepmag separators deliver uniform, constant magnetic force throughout the separation volume, which avoids bead aggregation, improves recovery, and enhances reproducibility compared to conventional magnetic systems that generate non-homogeneous forces.
What is the QUALITANCE monitoring system and why is it important?
QUALITANCE is Sepmag’s integrated real-time process monitoring software and sensor platform. It tracks separation performance, compares results against defined protocols, identifies deviations early, and enables traceable digital records for QA/QC, audits, and regulatory compliance.
Which workflows and applications benefit most from Sepmag Large Volume Separators?
These systems are ideal for large-scale nucleic acid extraction, protein purification, cell isolation, and diagnostic reagent production. They are also suitable for broader biomanufacturing processes where reproducibility, yield, and scalability matter.
Can Sepmag separators handle both glass and plastic vessels?
Yes. The Sepmag Q Series is optimized for glass bioprocess bottles, while the Sepmag N Series provides equivalent performance for plastic vessels, offering flexibility in workflow integration.
How do large volume separators improve product quality and process control?
By providing standardized, reproducible workflows with real-time monitoring and traceability, Sepmag separators enhance product quality and facilitate validation and compliance across regulated production environments.
What are the core benefits of Sepmag’s large volume separators?
Key benefits include elimination of assay variability, highest recovery of biomolecules and beads, minimal aggregation, easy scale-up with no revalidation needed, comprehensive quality assurance, and safe, low-maintenance operation.
How does Sepmag support customers beyond the product?
Sepmag offers product notes, technical support, and application guidance to help integrate large volume separators into existing workflows and to maximize throughput, consistency, and regulatory readiness.
Are Sepmag Large Volume Magnetic Bead Separators used by leading life science organizations?
Yes. Sepmag’s technology is trusted by major life science and diagnostics companies worldwide, reflecting proven performance and reliability at scale.
Ready to Improve Your Magnetic Separation Workflow?
Whether you’re producing diagnostic assays, isolating therapeutic cells, or purifying biomolecules, Sepmag Q and N magnetic bead separators offer a scalable, validated solution for high-volume magnetic bead separation.
Ready to explore the right system for your application or request a demo to see Sepmag Q and N in action?
