Sepmag is a Barcelona-based manufacturer of magnetic bead separation systems for life science, biotechnology and IVD applications, from laboratory research to large-volume GMP manufacturing.
Our systems help improve recovery, reduce process variability, define the separation endpoint and scale magnetic bead workflows from small-volume research to large-volume production.
Reproducible separation. Real-time process monitoring. Scalable from R&D to GMP manufacturing.
How Sepmag Improves Magnetic Bead Separation
Magnetic separation should not be an uncontrolled step in your workflow.
Sepmag makes magnetic bead separation controlled, measurable and scalable, helping you improve process performance from development through manufacturing.
Improve Bead and Target Recovery
Capture magnetic beads reliably before removing the liquid phase and determine the appropriate separation endpoint to reduce bead and target loss.
Improve Reproducibility
Maintain controlled magnetic separation conditions from run to run and reduce variability caused by magnetic conditions and operator judgement.
Measure Magnetic Bead Separation
Follow separation kinetics in real time. Determine the endpoint, compare runs and identify changes in bead or process behavior.
Scale Magnetic Bead Processes with Confidence
Transfer controlled magnetic separation conditions from research to process development, pilot production and GMP manufacturing.
Magnetic Bead Separation Systems from Research to GMP Manufacturing
Your magnetic bead process may start with milliliters and eventually reach liters.
Sepmag provides scalable magnetic bead separation equipment that allows the separation process to evolve with your workflow instead of being redesigned every time the volume increases.
Research & Analytical Magnetic Bead Separators
Small-volume systems for research, assay development and analytical workflows involving magnetic beads.
Applications include DNA and RNA purification, cell isolation, protein purification, IVD and diagnostic assay development.
The portfolio includes systems optimized for magnetic nanoparticles and magnetic microparticles, depending on the application and bead size.
Sepmag systems: CELL · LAB · LITE
Process Development & Scale-Up Systems
Develop, characterize and optimize your magnetic bead separation process under controlled conditions before transferring it to production.
Generate objective separation data and maintain a consistent separation approach as working volumes increase.
Sepmag systems: Sepmag A
Large-Volume & GMP Magnetic Bead Separation Systems
Scale magnetic bead separation to manufacturing while maintaining controlled magnetic conditions, reproducible performance and objective process monitoring.
Sepmag provides large-volume magnetic bead separators for glass and single-use vessels, with solutions designed for automated and regulated production environments. Real-time monitoring supports process documentation, quality control, validation and consistent batch-to-batch performance.
Sepmag systems: Sepmag Q · Sepmag N
Magnetic Bead Separation for Your Application
Sepmag magnetic bead separation systems support a wide range of magnetic bead-based workflows.
The application may change, but the objective is the same: recover the beads reliably, protect the target and make the separation process reproducible.
DNA & RNA Purification
Improve magnetic bead recovery and separation consistency in DNA and RNA extraction, sample preparation, PCR and sequencing workflows.
Cell Isolation
Use controlled magnetic separation conditions for magnetic bead-based cell isolation while protecting cell recovery, viability and functionality.
Protein & Biomolecule Purification
Reduce losses during magnetic separation and improve recovery in protein, antibody and biomolecule purification workflows.
Diagnostic Assays
Make magnetic separation a controlled and reproducible part of diagnostic assay development, sample preparation and reagent manufacturing.
Scale-Up & GMP Manufacturing
Transfer magnetic bead separation from process development to large-volume production while maintaining reproducible separation conditions.
Why Sepmag Magnetic Bead Separators Are Different
Magnetic bead separation performance depends on more than placing a vessel next to a magnet.
For demanding workflows, you need to know how the beads are being separated and when the separation is complete.
Sepmag combines constant magnetic force with real-time separation monitoring to make the magnetic separation step controlled and measurable.
Constant Magnetic Force
Sepmag magnetic bead separators use a cylindrical configuration around the vessel to generate 360° constant magnetic force.
Magnetic beads therefore migrate toward the vessel walls under controlled radial separation conditions.
This helps create predictable bead movement, reduce separation-related variability and maintain consistent separation conditions as processes are scaled.
Real-Time Magnetic Bead Separation Monitoring
A clear sample tells you how the process looks at the end. It does not tell you how the beads behaved during separation.
Sepmag monitoring technology continuously tracks changes in the magnetic bead suspension and generates a separation curve, providing objective data on separation kinetics and endpoint.
This allows you to:
- determine an objective separation endpoint;
- compare runs, batches and magnetic bead lots;
- detect changes in separation kinetics;
- optimize and standardize magnetic bead protocols;
- support process transfer, validation and quality control;
- document separation performance.
For GMP manufacturing, QUALITANCE data can be managed within Sepmag’s 21 CFR Part 11-ready and EU GMP Annex 11-aligned software environment, supporting traceable separation records and regulated manufacturing workflows.
Instead of relying only on visual judgement or a predefined waiting time, you can measure, document and compare the magnetic separation process itself.
Controlled. Measurable. Scalable.
Constant magnetic force controls the separation conditions.
Real-time monitoring measures what happens during separation.
Together, they allow magnetic bead separation to be optimized, reproduced, documented and scaled from research to manufacturing.
Used by Life Science and Diagnostic Companies Worldwide
Sepmag magnetic bead separation systems are used in research, biotechnology, diagnostics and manufacturing workflows worldwide.
Sepmag: Specialists in Magnetic Bead Separation
Sepmag specializes in magnetic bead separation systems for users of magnetic beads.
We help life science, biotechnology and diagnostic organizations make magnetic bead separation more controlled, reproducible and scalable.
Our systems cover the complete process-development path—from laboratory research and assay development to process scale-up and large-volume GMP manufacturing.
This specialization allows us to support customers not only in selecting a separator, but also in understanding, optimizing and scaling the magnetic separation step within their process.
We help you turn magnetic bead separation from an empirical step into a controlled, measurable and scalable process.
Tell Us About Your Magnetic Bead Workflow
Are you trying to improve recovery, reduce variability, determine the correct separation endpoint or scale a magnetic bead process to production?
Tell us:
your magnetic bead type;
your working volume;
your vessel;
your application;
and your current separation challenge.
We can help you identify the appropriate magnetic separation approach and Sepmag system.
