Small Volume Magnetic Bead Separators for Research & Analytical Workflows
Sepmag LITE, LAB and CELL are small volume magnetic bead separators designed for research, assay development and analytical workflows.
Choose the system according to your application: LITE for protein and antibody purification, LAB for DNA and RNA extraction, and CELL for cell isolation.
Compatible with standard laboratory tubes and working volumes from approximately 0.5 to 35 mL.
Choose the Right Small Volume Magnetic Bead Separator
The right Sepmag system depends primarily on your application and magnetic bead type.
Sepmag LITE — For Protein, Antibody and Biomolecule Purification
Choose Sepmag LITE for small-volume protein and biomolecule purification workflows.
It is particularly suited to protein and antibody purification, immunoassays and IVD assay development where high recovery and reproducible separation are important.
Tube capacity: 3–4 tubes simultaneously
Compatible tubes: 1.5, 2, 15 and 50 mL
Working volume: approximately 0.5–35 mL
Sepmag LAB — For DNA & RNA Purification
Choose Sepmag LAB for magnetic bead-based nucleic acid extraction.
It is designed for DNA and RNA purification workflows where efficient bead recovery directly affects yield, purity and downstream analytical performance.
Typical applications include genomic DNA, plasmid DNA, RNA, PCR/qPCR sample preparation and sequencing workflows.
Tube capacity: 1–4 tubes simultaneously
Compatible tubes: 1.5, 2, 15 and 50 mL
Working volume: approximately 0.5–35 mL
Sepmag CELL — For Cell Isolation
Choose Sepmag CELL for cell isolation and enrichment workflows using magnetic nanoparticles.
It is designed for applications where cell recovery, viability and functionality must be preserved for subsequent analysis or culture.
Typical applications include immune cell isolation, stem cell workflows, rare cell enrichment, flow cytometry and cell culture.
Tube capacity: 1 tube
Compatible tubes: 1.5, 2, 15 and 50 mL
Working volume: approximately 0.5–35 mL
What You Gain in Small Volume Magnetic Bead Separation
Improve Recovery
Incomplete or inconsistent bead collection can lead to loss of valuable DNA, RNA, proteins, antibodies or cells.
Controlled separation helps maximize bead recovery and reduce sample loss during aspiration and washing steps.
Improve Reproducibility
Use defined magnetic separation conditions instead of depending on bead position or operator judgement.
This helps reduce experiment-to-experiment variability and makes protocols easier to reproduce between users and laboratories.
Reduce Bead Aggregation
Avoid excessive bead compaction during separation.
Easier resuspension improves handling between washing and elution steps and helps maintain consistent process performance.
Understand Your Separation Process
Magnetic separation time depends on the beads, sample conditions and protocol.
Real-time monitoring allows you to see how the beads actually separate instead of relying only on a fixed waiting time or visual inspection.
Optimize Protocols with Data
Separation curves make it possible to compare experimental conditions, bead lots and protocols objectively.
This is particularly useful during assay development, troubleshooting and method optimization.
Measure Magnetic Bead Separation in Real Time
Sepmag MONITOR provides real-time optical monitoring of the magnetic bead separation process with LITE, LAB and CELL systems.
Instead of recording only a separation time, you can measure the complete separation kinetics.
This allows you to compare runs, determine an objective endpoint, evaluate protocol changes and detect differences in bead behavior.
Compatible Tube Sizes and Working Volumes
All three product families support common laboratory tube formats.
The correct separator is determined primarily by the application and magnetic beads, rather than sample volume alone.
For workflows beyond these volumes, Sepmag offers dedicated systems for process development, scale-up and GMP manufacturing.
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Which Sepmag Small Volume Separator Do I Need?
Sepmag LITE
Choose Sepmag LITE for protein, antibody and biomolecule purification.
Sepmag LAB
Choose Sepmag LAB for DNA and RNA extraction and purification.
Sepmag CELL
Choose Sepmag CELL for cell isolation workflows using magnetic nanoparticles.
All three systems support working volumes from approximately 0.5 to 35 mL using common laboratory tube formats.
Frequently Asked Questions
What is a small volume magnetic bead separator?
A small volume magnetic bead separator is a benchtop system designed to separate magnetic beads in laboratory-scale samples. Sepmag LITE, LAB and CELL support working volumes from approximately 0.5 to 35 mL.
What is the difference between Sepmag LITE, LAB and CELL?
The systems are optimized for different workflows. LITE is designed for protein and antibody purification, LAB for DNA and RNA purification, and CELL for cell isolation.
Which Sepmag system should I use for DNA or RNA extraction?
Use Sepmag LAB for magnetic bead-based DNA and RNA purification, including PCR, qPCR and sequencing sample preparation workflows.
Which Sepmag system should I use for cell isolation?
Use Sepmag CELL for cell isolation and enrichment workflows, particularly those using magnetic nanoparticles.
Find the Right Separator for Your Workflow
Tell us your:
Application → magnetic beads → tube format → working volume
We will help you identify the appropriate Sepmag system for your research or analytical workflow.
