Precise Magnetic Bead Separation for Small-Volume and Academic Applications
Achieve consistent, reproducible results with Sepmag’s small volume magnetic bead separators – engineered for reliability, ease of use, and research scalability.
Whether you’re working on immunoassays, nucleic acid extraction, or cell isolation, precise magnetic bead separation is critical for reproducibility, standardization, and high yield.
Sepmag’s small-volume systems provide real-time monitoring, avoid aggregation, and ensure uniform conditions across your magnetic beads.
Understand and reproduce your separation process
Designed for academic labs and small-scale bioprocesses
Compatible with common research workflows
Sepmag Product Selector
We offer three products suitable for small volume magnetic bead separation, suitable for R&D and academic applications:
Sepmag LITE
Suitable for IVD development & Protein purification
- Designed for small-volume immunoassays
- Prevents aggregation for cleaner separations
- Reproducible workflows for assay development
Sepmag LAB
Suitable for Nucleic Acid Extraction
- Precise magnetic control for DNA/RNA workflows
- Excellent yield and purity
- Ideal for PCR, qPCR, and library prep
Sepmag CELL
Suitable for Cell Isolation
- Gentle separation for sensitive cell types
- Constant magnetic force exposure avoids cell damage
- Scalable protocols for flow cytometry or culture
Core Benefits
The Sepmag LITE, LAB and CELL small volume magnetic bead separators benefit from the same powerful design principles that underpin reliable magnetic bead separation. All models are engineered to deliver consistent, high-quality results from early-stage research to standardized assay development.
Reproducibility
Ensure consistent results across labs and experiments
Real-Time Monitoring
Visualize separation with MONITOR software + hardware
Standardization
Develop validated, transferable protocols
High Recovery
Minimize sample loss, maximize purity and yield
Research Ready
Adaptable for academic budgets and bench-scale needs
No Aggregation
Equal conditions for all beads = better results
Sepmag LITE
Sepmag LITE is purpose-built for small-volume workflows such as in vitro diagnostic (IVD) assay development and protein purification and is an ideal solution for benchtop use in university labs and biotech incubators.
The consistent magnetic force distribution ensures that all magnetic beads are exposed to the same conditions to prevent clumping and aggregation – common issues that compromise assay performance. Researchers benefit from higher recovery of target biomolecules, minimizing sample loss and improving downstream assay performance, and are particularly suited to test and optimize protocols with a focus on accuracy and reproducibility.
Sepmag LITE Technical Information
Sepmag LITE | |
Magnetic Force | Standard, optimized for gentle yet effective separations |
Tube Capacity | 3-4 tubes simultaneously |
Dimensions | Ø 139 mm × 77 mm |
Weight | 1.5 kg |
Compatible Tube Sizes & Volumes | |
1.5 ml tubes | 0.5-1.5 ml |
2 ml tubes | 1-2 ml |
15 ml tubes | 4.5-9 ml |
50 ml tubes | 17.5-35 ml |
Sepmag LAB
Sepmag LAB is optimized for high-efficiency nucleic acid extractions, supporting workflows such as genomic DNA, plasmid DNA, and RNA purification. Its uniform magnetic force ensures clean, reproducible separation of nucleic acid-bound beads, which is critical for sensitive downstream applications like PCR, qPCR, and next-generation sequencing (NGS). Designed for academic labs and research institutions, the LAB system bridges the gap between benchtop convenience and high-performance magnetic bead separation.
Researchers benefit from the combination of high yield, low sample loss, and compact footprint makes Sepmag LAB particularly valuable for labs processing multiple small-volume samples, especially when data quality and consistency are non-negotiable.
Sepmag LAB Technical Information
Sepmag LAB | |
Magnetic Force | Enhanced, suitable for efficient nucleic acid capture |
Tube Capacity | 1-4 tubes simultaneously |
Dimensions | Ø 137 mm × 77 mm |
Weight | 0.9 kg |
Compatible Tube Sizes & Volumes | |
1.5 ml tubes | 0.5-1.5 ml |
2 ml tubes | 1-2 ml |
15 ml tubes | 4.5-9 ml |
50 ml tubes | 17.5-35 ml |
Sepmag CELL
Sepmag CELL is engineered specifically for cell separation applications that require both precision and care – such as isolating rare cell populations or working with fragile cell types. Its powerful yet uniform magnetic ensures that all cells are subjected to the same separation conditions, which reduces the risk of aggregation and preserves cell viability.
Whether you’re working on immunology, stem cell research, or primary cell isolation, the CELL system ensures reproducible and high-yield recovery which is particularly valuable where cell quality directly impacts the success of follow-up experiments like flow cytometry, cell culture, or molecular profiling.
Sepmag CELL Technical Information
Sepmag LAB | |
Magnetic Force | Maximum, designed for efficient cell separation |
Tube Capacity | 1 tube at a time |
Dimensions | Ø 137 mm × 82 mm |
Weight | 1.8 kg |
Compatible Tube Sizes & Volumes | |
1.5 ml tubes | 0.5-1.5 ml |
2 ml tubes | 1-2 ml |
15 ml tubes | 4.5-9 ml |
50 ml tubes | 17.5-35 ml |
Track, Understand, and Improve Every Separation with Sepmag MONITOR
Real-time monitoring. Quantifiable results. Reproducible science.
Sepmag MONITOR is our integrated software and hardware solution that gives you full visibility into the magnetic bead separation process. Instead of relying on assumptions or visual estimations, MONITOR provides real-time optical tracking of bead movement – turning every experiment into a data-rich process that can be analyzed, standardized, and optimized.
Featuring the key benefits:
Real-time tracking of magnetic bead migration using optical sensors
Quantitative measurement of separation dynamics for data-driven optimization
Reproducibility across runs, users, and protocols
Protocol validation and standardization across labs, sites, or team members
User-friendly software interface, with data export for further analysis
Compact integration with LITE, LAB, and CELL systems
Clients
Trusted by leading life science companies:
Questions & Answers
What are Small Volume Magnetic Bead Separators?
Small volume magnetic bead separators are benchtop systems engineered for precise and reproducible magnetic bead separation at research and academic scales, typically from microliters to tens of milliliters. They support workflows in immunoassays, nucleic acid extraction, protein purification, and cell isolation in university and biotech labs.
Which Sepmag products are available for small volume and academic applications?
Sepmag offers three core systems tailored for small volume workflows:
- Sepmag LITE — optimized for in-vitro diagnostic (IVD) development and protein purification.
- Sepmag LAB — designed for efficient nucleic acid extraction (DNA/RNA).
- Sepmag CELL — engineered for gentle cell isolation with preserved viability.
How do Sepmag small volume separators improve reproducibility in the lab?
Sepmag systems deliver a consistent magnetic separation environment that avoids bead aggregation and ensures all magnetic beads experience the same conditions. This uniformity across runs supports reproducibility within and between research teams and across multiple experiments.
What role does real-time monitoring play in Sepmag separators?
The integrated MONITOR software and optical hardware provides real-time tracking of bead movement, enabling users to visualize and quantify separation dynamics. This data-rich visibility helps optimize protocols, standardize methods, and generate reliable, reproducible results in academic workflows.
What specific academic applications benefit from Sepmag small volume separators?
Sepmag small volume systems support a broad range of academic research activities, including:
- Development and optimization of immunoassays
- Nucleic acid purification (PCR, qPCR, sequencing prep)
- Protein capture and purification workflows
- Isolation of sensitive or rare cell populations for downstream analysis.
Why is avoiding bead aggregation important for small volume workflows?
Bead aggregation can reduce magnetic bead surface area available for binding targets, compromise separation efficiency, and lead to inconsistent yields. Sepmag’s design maintains uniform magnetic force distribution to prevent aggregation, improving recovery, purity, and overall data quality.
Can Sepmag separators support method standardization across labs or site locations?
Yes. The combination of uniform magnetic conditions and real-time quantification allows researchers to validate, transfer, and reproduce protocols across labs or research groups, enhancing collaborative consistency and reducing variability.
Are Sepmag small volume separators suitable for sensitive cell types?
The Sepmag CELL model is specifically engineered for cell isolation workflows that require gentle magnetic conditions to preserve cell viability and functionality, which is critical for downstream assays like flow cytometry or culture.
What are the core benefits of using Sepmag small volume systems?
Core benefits include: reproducible results across experiments, real-time visibility into separation performance, standardized and transferable protocols, high recovery and yield with minimal sample loss, and compatibility with common research workflows and tube formats.
How does Sepmag support researchers beyond the product itself?
Sepmag provides detailed product notes, application guidance, and technical support to help laboratories integrate magnetic bead separation into existing workflows, optimize protocols, and achieve consistent performance in research and academic settings.
Ready to Improve Your Magnetic Separation Workflow?
Whether you’re optimizing diagnostic assays, isolating cells, or extracting nucleic acids, Sepmag small volume magnetic bead separators offer the reproducibility, visibility, and performance today’s researchers demand.
Get in touch today to explore the best solution for your lab – or request a personalized demo to see Sepmag in action.
