Magnetic Bead Separators for Research, Scale-Up and Manufacturing
Sepmag magnetic bead separators provide reproducible magnetic separation for applications involving magnetic nanoparticles and microparticles, from laboratory research and process development to GMP manufacturing.
Our systems combine constant magnetic force with real-time separation monitoring capabilities to improve bead recovery, process consistency and scalability. Explore our product range and select the appropriate system according to your application, working volume, vessel type and automation requirements.
Choose Your Product Family
Research & Analytical Systems
For small-volume research and assay development
Choose this range if you work with laboratory tubes and need a system optimized for a specific magnetic bead application.
Sepmag CELL
For cell isolation workflows using magnetic nanoparticles.
Sepmag LAB
For DNA and RNA purification using magnetic microparticles.
Sepmag LITE
For protein, antibody and biomolecule purification.
Typical working volumes: approximately 0.5–35 mL
Process Development & Scale-Up Systems
For process optimization, scale-up and pilot workflows
Choose Sepmag A when your process is moving beyond small laboratory volumes and you need to develop or optimize the separation step before manufacturing.
Suitable for:
- Process development
- Protocol optimization
- Scale-up studies
- Pilot production
- Bottles and larger laboratory vessels
Typical volumes: up to 400 mL
GMP Manufacturing Systems
For production-scale magnetic bead separation
Choose this range when the magnetic separation step is part of a manufacturing process and requires larger vessels, production-scale handling and GMP-compatible configurations.
Sepmag Q
For processes using glass vessels.
Sepmag N
For processes using plastic or single-use vessels.
Suitable for:
- Pilot and manufacturing batches
- Liter-scale magnetic bead separation
- GMP environments
- Automated or semi-automated production
Automation Systems
For high-throughput magnetic bead workflows in 96-well plates
Choose Sepmag Smartplate 96 when you need to integrate magnetic bead separation into an automated or high-throughput laboratory workflow.
Designed for standard V-bottom 96-well plates, Smartplate 96 is suitable for applications such as:
- DNA & RNA purification
- Diagnostic workflows
- Cell isolation
- High-throughput sample processing
- Laboratory automation
It can be integrated into existing automated systems through a USB serial protocol.
Customized & OEM Systems
For non-standard vessels, special process requirements and integration into third-party equipment.
Sepmag develops customized magnetic bead separators for specific vessel geometries, working volumes, bead properties and automation requirements, including OEM applications.
Choosing the Right Sepmag System
Why Choose Sepmag Magnetic Bead Separators?
Unlike conventional magnetic racks, Sepmag systems use controlled radial magnetic separation to apply constant magnetic force across the working volume. This helps deliver reproducible bead recovery and supports consistent separation conditions during scale-up.
Real-time separation monitoring, available with supported systems, makes magnetic bead separation measurable, allowing users to optimize protocols, define separation endpoints and compare process performance.
Frequently asked questions about Sepmag magnetic bead separators
How do I choose the right Sepmag magnetic bead separator?
The appropriate system depends on the magnetic bead application, bead properties, working volume, vessel format and process stage. Sepmag offers laboratory separators for research, intermediate systems for process development, large-volume systems for GMP manufacturing and solutions for automated workflows.
Can Sepmag magnetic bead separation systems support scale-up from research to manufacturing?
Yes. Sepmag offers systems for different stages of process development and production, from laboratory tubes to liter-scale manufacturing vessels. Constant magnetic force provides controlled separation conditions, while monitoring capabilities help characterize separation performance and support process transfer.
Can Sepmag separators be used with both magnetic nanoparticles and microparticles?
Yes. Sepmag offers systems suited to workflows involving magnetic nanoparticles and microparticles. For example, Sepmag CELL is designed for cell isolation using magnetic nanoparticles, while Sepmag LAB is optimized for nucleic acid purification using magnetic microparticles. The appropriate separator depends on the bead characteristics, sample and application.
