Biofunctionalization of Magnetic Beads in Chemiluminescent (CLIA)
- Title
- Biofunctionalization of Magnetic Beads in Chemiluminescent (CLIA)
- Author
- Lermo, Anabel
- Publisher
- Sepmag
- City and year
- Barcelona, 2021
- Format
- Number of pages
- 18
- Volume (MB)
- 1,05
- Figures
- 14 graphs and 3 photos
- Thematic interest
- Quality Control – Monitor
From Design to Scale-Up: A Practical Guide to CLIA with Magnetic Beads
Chemiluminescent immunoassays (CLIA) are a cornerstone of modern diagnostics, valued for their sensitivity, wide dynamic range, and straightforward detection methods. When paired with magnetic beads, CLIA becomes even more powerful—offering higher specificity, streamlined workflows, and seamless automation for clinical and industrial applications.
The free ebook Biofunctionalization of Magnetic Beads in Chemiluminescent (CLIA) gives researchers and developers a clear roadmap to design, optimize, and scale assays effectively. From understanding chemiluminescence fundamentals to mastering assay formats and scale-up strategies, this guide bridges science and practice to help you achieve consistent results.
Inside this free guide, you’ll discover:
- How magnetic beads enhance CLIA sensitivity and specificity.
- Strategies for assay design across simple and complex formats.
- Chemical vs. biological bead functionalization approaches.
- Best practices for conjugation and tracer optimization.
- Key considerations for reagent stability, contamination control, and scaling up.
- Insights on current CLIA kits and automation platforms.
Take the guesswork out of CLIA development and ensure reproducibility at every stage.
Download your free copy today and learn how to optimize CLIA assays with magnetic beads for consistent, high-performance results.
Download it here
Chapters of ‘Biofunctionalization of Magnetic Beads in Chemiluminescent (CLIA)’
- Overview on Chemiluminescent immunoassay (CLIA)
- Magnetic beads in CLIA
- Preliminary considerations for CLIA design
- Most common assay formats
- Guide for successful magnetic bead conjugation
- Tracer Optimization
- CLIA-label protein conjugation
- Guide for optimizing CLIA performance and scaling-up
- Aspects of available CLIA kits in the market
- Limitations and perspectives
Author: Anabel Lermo
Dr. Anabel Lermo holds a PhD in Chemistry from the Universitat Autònoma de Barcelona (UAB) and is an experienced Research Scientist specializing in In-Vitro Diagnostics (IVD). She began her career with postdoctoral research at UAB’s Analytical Chemistry Division, focusing on immunoassay development for biosensor design. She then joined Biokit, part of the Werfen Group, where for seven years she contributed to the development of chemiluminescent immunoassays for automated platforms in the field of infectious diseases. More recently, she worked at Pragmatic Diagnostics, leading the design of innovative assays that integrate immunometric technologies with advanced analytical platforms for the IVD industry.
