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scaling biomagnetic separation processes, magnetic separation process

Set up of Magnetic Bead Separation Production Processes

Scientists in academic research labs and pharmaceutical labs perform magnetic separation process with magnetic bead kits for immunoassays and separation science. Doctors, lab technicians and scientists use magnetic beads in IVD kits as molecular diagnostics devices.

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Even though scientists typically use these beads at any given time in relatively small quantities, once the kit hits the market and is a product that has proven useful, the production volume for the kit must necessarily increase to meet demand. One needs to provide kits to many hospitals and labs globally and therefore one needs a cost-effective way to produce magnetic beads.

But since scientists only need a very small quantity of beads for any given use, why is production a problem?

Normal lab and development techniques, while effective in the initial development and testing stage, are not effective in coping with the increased costs and attention to quality necessary in ramping up production volumes. Often there are in-lot inconsistencies, a great deal of material loss (from both beads and biomolecules), and aggregation of beads. In addition, when one has to use larger magnets, there are greater safety and health risks that must be considered.

Scaling up a production process is not trivial. Costs increase dramatically, processing becomes more and more complex, and quality assurance is difficult to control. As a result, one can experience product delivery delays which can create anxiety at the managerial level.

When a production facility is efficient, it will not waste necessary time, effort and resources.

If you found this post about using Magnetic Bead Separation for production useful, don’t forget to check these related posts:

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Lluis M. Martínez | SEPMAG Chief Scientific Officer

Founder of SEPMAG, Lluis holds a PhD in Magnetic Materials by the UAB. He has conducted research at German and Spanish academic institutions. Having worked in companies in Ireland, USA and Spain, he has more than 20 years of experience applying magnetic materials and sensors to industrial products and processes. He has filed several international patents on the field and co-authored more than 20 scientific papers, most of them on the subject of magnetic particle movement.

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